| Silver City, Iowa | Silver City, Mississippi | Silver Cliff, Colorado |
| Silver Cliff, Wisconsin | Silver Creek Township, Michigan | Silver Creek, Mississippi |
| Silver Creek, Missouri | Silver Creek, Nebraska | Silver Creek, New York |
| Silver cyanide | Silver diammine fluoride | Silver fulminate |
| Silver Grove, Kentucky | Silver halide | Silver hexafluorophosphate |
| Silver iodate | Silver iodide | Silver Lake, Kansas |
| Silver Lake, Minnesota | Silver Lake, Wisconsin | Silver Linings Playbook |
| Silver molybdate | Silver Nano | Silver nanoparticle |
| Silver nitrate | Silver Plume, Colorado | Silver ratio |
| Silver Springs, New York | Silver sulfate | Silver sulfide |
| Silver telluride | Silver tetrafluoroborate | Silver Wolf Award |
| Silver(I) fluoride | Silver(I) selenide | Silver(I,III) oxide |
| Silver(II) oxide | Silver-breasted Broadbill | Silver-oxide battery |
| Silverbell | Silverfish | Silverlight |
| Silverthorne, Colorado | Silverton, Colorado | Silverton, Oregon |
| Silverton, Texas | Silvester II | Silvestre de Sacy |
| Silvestre Igoa | Silvestre Varela | Silvetia |
| Silvetia babingtonii | Silvetia compressa | Silvetia siliquosa |
| Silvia Navarro | Silvia Navarro (handballer) | Silviabadeh |
| Silviculture | Silvio Berlusconi | Silvio Marić |
| Silvio Micali | Silvio Piola | Silvis, Illinois |
| Silviu Bindea | Silviu Lung | Silvology |
| Silya Magnana | Silybum | Silybum eburneum |
| Silybum marianum | Silymarin | Sima Qian |
| Sima Yi | Simakan Rural District | Simaroubaceae |
| Simarouboideae | Simas Jasaitis | Simão Sabrosa |
| Siméon Denis Poisson | Simón Bolívar | Simón Díaz |
| Simón Lecue | Simba | Simbi Khali |
| SimCity | SimCity (1989 video game) | SimCity (2013 video game) |
| SimCity 2000 | SimCity 3000 | SimCity 4 |
| SimCity 4: Rush Hour | SimCity 64 | SimCity Creator |
| SimCity DS | SimCity DS 2 | SimCity Social |
| SimCity Societies | Simd | SIMD |
| Simencourt | Simeon Masaba | Simeon Saxe-Coburg-Gotha |
| Simeon Slavchev | Simfibrate | Simi Valley, California |
| Simian vacuolating virus 40 | Simian virus 40 | Simiiformes |
| Similac | Similarity (geometry) | Simile |
| Simin Behbahani | Simin Daneshvar | Simineh Rud Rural District |
| Simiyya | Simko Shikak | Simko Shikak revolt |
| Simla, Colorado | Simmondsia chinensis | Simnas |
| Simo Nikolić (footballer) | Simo Parpola | Simon & Schuster |
| Simon and Garfunkel | Simon Armitage | Simon Baker |
| Simon Bamberger | Simon Callow | Simon Cox (footballer, born 1987) |
| Simon Davies (footballer, born 1979) | Simon de Montfort, 6th Earl of Leicester | Simon Donaldson |
| Simon Elliott | Simon Flexner | Simon Kinberg |
| Simon Kjær | Simon Kuznets | Simon Mignolet |
| Simon Newcomb | Simon Ochley | Simon Ockley |
| Simon Pegg | Simon Plouffe | Simon Poulsen |
| Simon Pouplin | Simon Rolfes | Simon Stevin |
| Simon van der Meer | Simon's Cat | Simona Halep |
| Simone (2002 film) | Simone Barone | Simone Bentivoglio |
| Simone Bolelli | Simone de Beauvoir | Simone Del Nero |
| Simone Inzaghi | Simone Padoin | Simone Pepe |
| Simone Perrotta | Simone Pesce | Simone Scuffet |
| Simone Signoret | Simone Thiero | Simone Tiribocchi |
| Simone Verdi | Simone Vergassola | Simone Weil |
| Simone Zaza | Simonetta Sommaruga | Simonides of Ceos |
| Simonton, Texas | Simony | Simoom |
| Simorgh (rocket) | Simorhinella | Simpatico |
| Simple columnar epithelium | Simple DirectMedia Layer | Simple English Wikipedia |
| Simple eye in invertebrates | Simple group | Simple harmonic motion |
| Simple Linux Utility for Resource Management | Simple living | Simple machine |
| Simple Mail Transfer Protocol | Simple Network Management Protocol | Simple polygon |
| Simple series | Simple-type schizophrenia | Simplemente María |
| SimpleText | Simplex algorithm | Simplex Nthala |
| Simplified Chinese character | Simplified molecular input line entry specification | Simplified molecular-input line-entry system |
| Simpson and Delilah | Simpson County, Kentucky | Simpson Desert |
| Simpson's rule | Simpson, Illinois | Simpson, Kansas |
| Simpson, North Carolina | Simpsonville, Kentucky | Simpsonville, South Carolina |
| Sims | SIMS Co., Ltd. | Sims Township, Michigan |
| Sims, Illinois | Simula | Simulated annealing |
| Simulation | Simulation video game | SimulationX |
| Simulfix | Simuliidae | Simulink |
| Simultaneity | Simultaneous game | Simultaneous localization and mapping |
| Simvastatin | Sin | Sin by Silence |
| Sin City (film) | Sin City: A Dame to Kill For | Sin Li Mo |
| Sin Yong-nam | Sin-Itiro Tomonaga | Sina Corp |
| Sina Weibo | Sina, Iran | Sina.com |
| Sinai insurgency | Sinai peninsula | Sinai, South Dakota |
| Sinan Antoon | Sinan Bolat | Sinan Güler |
| Sinan ibn Thabit | Sinan Pasha Mosque (Damascus) | Sinan Pasha Mosque (Istanbul) |
| Sinan Pasha Mosque (Kaçanik) | Sinan Pasha Mosque (Prizren) | Sinan Tuzcu |
| Sinapis | Sinapis alba | Sinapis arvensis |
| Sinapis nigra | Sinān ibn al-Fatḥ | Sinbad: Legend of the Seven Seas |
| Since You Went Away | Sincere voting | Sinciput |
| Sinclair Lewis | Sinclair, Wyoming | Sinclairville, New York |
| Sind ibn Ali | Sindbis virus | Sindel |
| Sindhi language | Sine | Sine qua non |
| Sine wave | Sineh Sar | Sinemurian |
| Sing (2016 film) | Sing for the Moment | Sing If You Can |
| Sing Sing | Singapore | Singapore Airlines |
| Singapore Airshow | Singapore Botanic Gardens | Singapore Changi Airport |
| Singapore dollar | Singapore Strait | Singapore strategy |
| Singapura cat | Singe | Singer-songwriter |
| Singh Is Bliing | Singham | Singham Returns |
| Singing | Singing Revolution | Single (music) |
| Single crystal | Single molecule fluorescent sequencing | Single parent |
| Single person | Single player | Single point of failure |
| Single responsibility principle | Single umbilical artery | Single UNIX Specification |
| Single-cylinder engine | Single-elimination tournament | Single-gene disorder |
