| Scottish Gaelic | Scottish Oceanographical Laboratory | Scottish Parliament Building |
| Scottish Premier League | Scottish Standard English | Scotts Hill, Tennessee |
| Scotts Mills, Oregon | Scottsburg, Indiana | Scottsville, Kansas |
| Scottsville, Kentucky | Scottsville, New York | Scottville, Illinois |
| Scottville, Michigan | Scotty 2 Hotty | Scout Association of Croatia |
| Scout Association of Uzbekistan | Scouting | Scouting and Guiding Federation of Turkey |
| Scouting and Guiding in Albania | Scouting in popular culture | Scouting in Somalia |
| Scouting Ireland | Scouting Nederland | Scouting sex abuse cases |
| Scoutisme Français | Scouts Australia | Scouts d'Andorra |
| Scouts Lao | Scoville scale | Scrabble |
| SCRAM | Scram | Scramble for Africa |
| Scramjet | Scranton, Arkansas | Scranton, Iowa |
| Scranton, Kansas | Scranton, North Dakota | Scranton, Pennsylvania |
| Scrap metal shredder | Scrapie | Scratch (programming language) |
| Scratch and sniff | Scream (film series) | Scream (سلسلة أفلام) |
| Scream 3 | Scream 4 | Scream Awards |
| Screamworks: Love in Theory and Practice | Screen Actors Guild Award | Screen Actors Guild Awards |
| Screen Awards | Screen burn-in | Screen grid |
| SCREEN mode | Screen printing | Screencast |
| Screening (medicine) | Screenplay | Screensaver |
| Screenshot | Screenshots of Windows software | Screenwriter |
| Screenwriting | Screven, Georgia | Screw |
| Screwdriver | Scribd | Script kiddie |
| Script.NET | Scripting language | Scroll |
| Scrolls of Abraham (Islam) | Scrooge McDuck | Scrophularia |
| Scrophularia aequilabris | Scrophularia alaschanica | Scrophularia auriculata |
| Scrophularia bicolor | Scrophularia buergeriana | Scrophularia californica |
| Scrophularia capusii | Scrophularia chasmophila | Scrophularia dentata |
| Scrophularia desertorum | Scrophularia diplodonta | Scrophularia elatior |
| Scrophularia fargesii | Scrophularia formosana | Scrophularia henryi |
| Scrophularia hypsophila | Scrophularia incisa | Scrophularia lanceolata |
| Scrophularia lucida | Scrophularia macrocarpa | Scrophularia mandarinorum |
| Scrophularia modesta | Scrophularia nodosa | Scrophularia occidentalis |
| Scrophularia pamirica | Scrophularia pauciflora | Scrophularia przewalskii |
| Scrophularia souliei | Scrophularia spicata | Scrophularia stylosa |
| Scrophularia umbrosa | Scrophularia urticifolia | Scrophularia villosa |
| Scrophulariaceae | Scrotum | Scrub tech |
| Scrubs (clothing) | Scrubs (TV series) | Scrum (development) |
| Scrum (software development) | Scrupulosity | SCSI |
| Scuba set | Scud | Scuderia Ferrari |
| Scudo | Sculpey | Sculptor Galaxy |
| Scurf | Scurvy | Scutellaria |
| Scutellaria barbata | Scutellaria galericulata | Scutellaria lateriflora |
| Scuttling of the French fleet in Toulon | Scylacosauria | Scylacosauridae |
| Scylacosaurus | Scyliorhinidae | Scyliorhinus tokubee |
| Scyllarus arctus | Scyphomedusae | Scyphozoa |
| Scytale | Scytalopus | Scytalopus acutirostris |
| Scytalopus affinis | Scytalopus argentifrons | Scytalopus atratus |
| Scytalopus bolivianus | Scytalopus canus | Scytalopus caracae |
| Scytalopus chocoensis | Scytalopus diamantinensis | Scytalopus femoralis |
| Scytalopus fuscus | Scytalopus griseicollis | Scytalopus latebricola |
| Scytalopus macropus | Scytalopus magellanicus | Scytalopus micropterus |
| Scytalopus novacapitalis | Scytalopus panamensis | Scytalopus parvirostris |
| Scytalopus petrophilus | Scytalopus robbinsi | Scytalopus sanctaemartae |
| Scytalopus speluncae | Scytalopus spillmanni | Scytalopus stilesi |
| Scytalopus superciliaris | Scytalopus unicolor | Scytalopus vicinior |
| Scytalopus zimmeri | Scythe | Scythia |
| Scythians | SD | SD Compostela |
| SDAT | Sde Dov Airport | SDEWES Centre |
| SDH | SDL | SDL Trados |
| SDRAM | SDS-page | SDS-PAGE |
| SDSL | SDTV | Se |
| Sea Cliff, New York | Sea eagle | Sea Eagle (missile) |
| Sea eagle missile | Sea fan | Sea foam |
| Sea level | Sea monk | Sea of Sand (film) |
| Sea otter | Sea pen | Sea Peoples |
| Sea salt | Sea Shadow (IX-529) | Sea skimming |
| Sea Skua | Sea squirt | Sea turtle |
| Sea wasp | SEA-ME-WE 4 | Seabird |
| Seabird Seeker | Seabiscuit (film) | Seaborgium |
| Seabrook, Texas | Sead Kolašinac | Seadragon Software |
| Seadrift, Texas | Seafood allergy | Seaford, Delaware |
| Seaforth, Minnesota | Seagoville, Texas | Seagram Building |
| Seagraves, Texas | Seahorse (software) | Seal |
| Seal (device) | Seal (emblem) | Seal dribble |
| Seal hunting | Seal of | Seal of Solomon |
| Seal of محافظة كفر الشيخ | Seal of غويانا الفرنسية | Sealant |
| Sealed birth records | Sealing wax | SEALs |
| Sealy, Texas | Seaman, Ohio | Seamless robe of Jesus |
| SeaMonkey | Seamus Deane | Seamus Heaney |
| Sean Astin | Sean Bean | Sean Combs |
| Sean Connery | Sean Davis (footballer) | Sean Faris |
| Sean Gullette | Sean Hayes (actor) | Sean Kilpatrick |
| Sean Murray (actor) | Sean O'Pry | Sean Patrick Thomas |
| Sean Paul | Sean Penn | Sean Richard O'Pry |
| Sean St Ledger | Sean Stone | Sean Yazbeck |
| Seann William Scott | SeaOrbiter | Seaplane |
| Seaport Centre | Search activity concept | Search algorithm |
| Search and rescue | Search engine indexing | Search engine optimization |
| Search for extraterrestrial intelligence | Searching for Sugar Man | Searcy, Arkansas |
| Searsburg, Vermont | SeaSeep | Seashell |
| Seasickness | Seaside, Oregon | Season |
| Season extension | Season finale | Seasonal breeder |
| Seasonal packaging | Seasonal thermal energy storage | SEAT |
| SEAT 1200 Sport | SEAT 124 | SEAT 124 Sport |
| SEAT 127 | SEAT 128 | SEAT 131 |
| SEAT 132 | SEAT 133 | SEAT 1400 |
| SEAT 1430 | SEAT 1430 Sport | SEAT 1500 |
| SEAT 600 | SEAT 800 | SEAT 850 |
| SEAT Alhambra | SEAT Altea | SEAT Altea Prototipo |
